| Autor: |
Bar M; Department of Medicine H, Tel Aviv Medical Center, Israel., Burke M, Isakov A, Almog C |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical gastroenterology [J Clin Gastroenterol] 1990 Oct; Vol. 12 (5), pp. 579-80. |
| DOI: |
10.1097/00004836-199010000-00018 |
| Abstrakt: |
Islet cell carcinoma frequently produces more than one chemical product, although its clinical expression is usually restricted to a single hormone. We describe an unusual patient who presented with full-blown metastasizing gastrinoma. He was treated with cimetidine for five years and then streptozotocin therapy, which resulted in a regression in hepatomegaly and a fall in serum gastrin levels. Following one year's therapy with streptozotocin, he was admitted in hyperinsulinemic hypoglycemic stupor. This appears to be the first reported case of a "shift" from clinical gastrinoma to insulinoma possibly related to prolonged streptozotocin therapy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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