[Radioembolization with (90)Y-labeled microspheres: post-therapeutic therapy validation with Bremsstrahlung-SPECT].

Autor: Grober OS; Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg A.ö.R, Otto-von-Guericke-Universität, Deutschland., Nultsch M, Laatz K, Ulrich G, Seidensticker R, Pethe A, Dudeck O, Pech M, Knoop BO, Ricke J, Amthauer H, Geworski L
Jazyk: němčina
Zdroj: Zeitschrift fur medizinische Physik [Z Med Phys] 2011 Dec; Vol. 21 (4), pp. 274-80. Date of Electronic Publication: 2011 Jun 29.
DOI: 10.1016/j.zemedi.2011.05.002
Abstrakt: During the last years angiographic Selective Internal Radiotherapy (SIRT) with (90)Y-labelled microspheres has become a common technique for the local-ablative treatment of cancer patients. SIRT is a palliative therapy concept for the treatment of liver malignancies. As a result of (90)Y-decay as β(-)-emitter without a concomitant gamma radiation, Bremsstrahlung imaging is needed to validate the distribution achieved by radioembolisation. This article demonstrates the method of imaging through phantom measurement and shows the advantages of post-therapeutic tomography by means of a patient study. Approaches for further optimization of Bremsstrahlung imaging are discussed.
(Copyright © 2011. Published by Elsevier GmbH.)
Databáze: MEDLINE
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