[The effect of cholino- and adrenoblockers on limbic-sympathetic evoked potentials].

Autor: Baklavadzhian OI, Eganova VS, Kasparova SR, Khudoian EA
Jazyk: ruština
Zdroj: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova [Fiziol Zh SSSR Im I M Sechenova] 1990 Apr; Vol. 76 (4), pp. 438-45.
Abstrakt: Effects of i.v. administration of cholino- and adrenergic blocking agents on limbic-sympathetic discharges of L2-L3 white rami, evoked by stimulation of the anterior, visceral area of the limbic cortex and on arterial blood pressure were studied in anesthetized cats. M- and N-cholinoreceptor blocking agents atropine and ganglerone do not induce any apparent changes in limbic-sympathetic discharge and the blood pressure level. Beta-adrenoreceptor blocking agent propranolol evoked a small fall of the blood pressure with no apparent changes of limbic-sympathetic discharges. Alpha-adrenoreceptor blocking agent phenotolamine evoked obvious drop of the blood pressure and, in two out of eight experiments, a marked increase of the amplitude of limbic-sympathetic evoked discharges. Neurochemical regulatory mechanism of limbic-spinal sympathetic activity are discussed.
Databáze: MEDLINE