[A rare case of huge aspergilloma developed within a lesion of pulmonary fibrosis secondary with a systemic scleroderma in an immunocompetent patient in Madagascar].

Autor: Rakotoson JL; Centre Hospitalier Universitaire d'Antananarivo, Antananarivo, Madagascar. jrakotoson@yahoo.fr, Vololontiana HM, Raherison RE, Andrianasolo R, Rakotomizao JR, Randria MJ, Rapelanoro RF, Andrianarisoa AC, Rajaona HR
Jazyk: francouzština
Zdroj: Bulletin de la Societe de pathologie exotique (1990) [Bull Soc Pathol Exot] 2011 Dec; Vol. 104 (5), pp. 325-8. Date of Electronic Publication: 2011 Jun 22.
DOI: 10.1007/s13149-011-0141-9
Abstrakt: We report a rare case of a huge aspergilloma developed within a bronchiectasis due to pulling by a pulmonary fibrosis of systemic scleroderma. The patient is a 58-year-old woman presenting a deterioration of the general state associated with repeating hemoptysis, dyspnea, dysphagia, sclérodactylia, generalized cutaneous sclerosis and Raynaud's phenomenon. There was no antecedent pulmonary tuberculosis. The patient had a pulmonary arterial hypertension complicated by a chronic pulmonary heart at the stage of right cardiac decompensation. Aspergillosis serology was positive and the immunological assessment confirmed scleroderma. The computed tomography showed a huge oblong opacity in a small round bell shape ("signe du grelot", Monad's sign) in the left upper lobe developed within a bronchiectasis, and a bilateral pulmonary fibrosis. Although surgery remains the recommended treatment of an aspergilloma, the management of our patient was medical in front of contra-indication for surgery. The evolution was marked by repeating hemoptysis and stability of the pulmonary lesions 2 years later. The management of this entity remains difficult and complicated; the prognosis is in general unfavourable and depends at the same time on the evolution of scleroderma and the aspergilloma infection.
Databáze: MEDLINE