Malignant jugulotympanic paraganglioma.

Autor: Johnstone PA; Department of Medicine, National Naval Medical Center, Bethesda, Md., Foss RD, Desilets DJ
Jazyk: angličtina
Zdroj: Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 1990 Sep; Vol. 114 (9), pp. 976-9.
Abstrakt: Jugulotympanic paragangliomas are neoplasms that arise in the jugular bulb (glomus jugulare tumor) or temporal bone (glomus tympanicum tumor). They are histologically similar to carotid body tumors; both are derived from extra-adrenal paraganglia. Of only 20 metastases reported, five had biopsy-proved bone involvement. We present a review of the literature of metastatic jugulotympanic paragangliomas and report a case that recurred locally with regional metastases 10 years after initial presentation and metastasized to spine 13 years later. Histologic data are reviewed, and potential treatment regimens are contrasted.
Databáze: MEDLINE