| Autor: |
Shaw FE Jr; Division of Viral and Rickettsial Diseases, Centers for Disease Control, Atlanta, GA 30333., Shapiro CN, Welty TK, Dill W, Reddington J, Hadler SC |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of public health [Am J Public Health] 1990 Sep; Vol. 80 (9), pp. 1091-4. |
| DOI: |
10.2105/ajph.80.9.1091 |
| Abstrakt: |
Hepatitis A continues to occur in cyclical community-wide epidemics on the Indian reservations of South Dakota. In June 1985 a population-based serosurvey for viral hepatitis involving 120 households was conducted at the Pine Ridge and Rosebud Sioux Indian reservations in South Dakota. The serosurvey was performed shortly after a large hepatitis A epidemic on the Pine Ridge reservation in 1983-84, and immediately before a large hepatitis A epidemic on the Rosebud reservation in 1985-86. The overall seroprevalence for antibodies to hepatitis A virus (anti-HAV) was 76.2 percent (Pine Ridge reservation 80.5 percent, Rosebud reservation 72.0 percent, relative risk = 1.12, 95 percent confidence interval = 1.01, 1.24). For age groups 0 to 4 years, 54.2 percent and 36.1 percent of children were seropositive at Pine Ridge and Rosebud, respectively. Seropositivity rose rapidly with age; by age 40, more than 90 percent of persons at both Pine Ridge and Rosebud were anti-HAV positive. Only 1.1 percent of persons tested were positive for hepatitis B markers. Anti-HAV seroprevalence rates in both communities are similar to rates observed in developing countries. The surprisingly high anti-HAV seroprevalence among young children at Rosebud, where clinical hepatitis A had been virtually absent in the previous seven years, indicates that high-grade silent transmission was taking place during the interepidemic period. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
