Impaired functional and hemodynamic response to graded exercise testing and its recovery in patients with subclinical hyperthyroidism.

Autor:	Vigário Pdos S; Laboratório de Fisiologia do Exercício, Escola de Educação Física e Desportos, Universidade Federal do Rio de Janeiro, RJ, Brazil. patriciavigario@yahoo.com.br, Chachamovitz DS, Teixeira Pde F, Santos MA, Oliveira FP, Vaisman M
Jazyk:	angličtina
Zdroj:	Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2011 Apr; Vol. 55 (3), pp. 203-12.
DOI:	10.1590/s0004-27302011000300005
Abstrakt:	Objective: To evaluate the functional and hemodynamic responses during exercise and its recovery in patients with subclinical hyperthyroidism (SCH). Subjects and Methods: A cross-sectional study was carried out with 29 patients on TSH-suppressive therapy with levothyroxine for thyroid carcinoma and 35 euthyroid subjects. All volunteers underwent a cardiopulmonary exercise testing on a treadmill and functional and hemodynamic variables were measured during exercise and its recovery. Results: SCH patients showed impaired functional response to exercise, marked by lower values for oxygen consumption and exercise duration in addition to premature achievement of the anaerobic threshold. Heart-rate and blood pressure recovery immediately after exercise were slower among SCH patients when compared to euthyroid subjects. Conclusion: SCH is associated with impaired functional and hemodynamic responses during exercise and its recovery.
Databáze:	MEDLINE
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