Molecular typing methods for outbreak detection and surveillance of invasive disease caused by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae, a review.

Autor: Harrison OB; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK., Brueggemann AB; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK., Caugant DA; Department of Bacteriology and Immunology, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO-0403 Oslo, Norway., van der Ende A; Academic Medical Center, Department of Medical Microbiology, Reference Laboratory for Bacterial Meningitis, PO Box 22660, 1100 DD Amsterdam, The Netherlands., Frosch M; Institut für Hygiene und Mikrobiologie, Universität Würzburg, Josef-Schneider Strasse 2, 97080 Würzburg, Germany., Gray S; Meningococcal Reference Unit, Health Protection Agency, PO Box 209, Clinical Sciences Building 2, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WZ, UK., Heuberger S; Österreichische Agentur für Gesundheit und Ernährungssicherheit GmbH, Bereich Humanmedizin, Institut für medizinische Mikrobiologie und Hygiene, Beethovenstraße 6, A-8010 Graz, Austria., Krizova P; National Reference Laboratory for Meningococcal Infections, National Institute of Public Health, Srobarova 48, Prague, Czech Republic., Olcen P; Department of Laboratory Medicine, Clinical Microbiology and Immunology, Orebro University Hospital, SE-701 85 Orebro, Sweden., Slack M; Respiratory and Systemic Infection Laboratory, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK., Taha MK; Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France., Maiden MCJ; Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK.
Jazyk: angličtina
Zdroj: Microbiology (Reading, England) [Microbiology (Reading)] 2011 Aug; Vol. 157 (Pt 8), pp. 2181-2195. Date of Electronic Publication: 2011 May 26.
DOI: 10.1099/mic.0.050518-0
Abstrakt: Invasive disease caused by the encapsulated bacteria Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae remains an important cause of morbidity and mortality worldwide, despite the introduction of successful conjugate polysaccharide vaccines that target disease-associated strains. In addition, resistance, or more accurately reduced susceptibility, to therapeutic antibiotics is spreading in populations of these organisms. There is therefore a continuing requirement for the surveillance of vaccine and non-vaccine antigens and antibiotic susceptibilities among isolates from invasive disease, which is only partially met by conventional methods. This need can be met with molecular and especially nucleotide sequence-based typing methods, which are fully developed in the case of N. meningitidis and which could be more widely deployed in clinical laboratories for S. pneumoniae and H. influenzae.
Databáze: MEDLINE
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