[Antibody formation in type A viral hepatitis].

Autor: Teokharova MP, Losev BB, Andonov AP, Draganov PI, Mineva EG
Jazyk: ruština
Zdroj: Voprosy virusologii [Vopr Virusol] 1978 Sep-Oct (5), pp. 539-44.
Abstrakt: Immune response to hepatitis type A antigen (HAAg) was measured by the passive hemagglutination test (PHA) and by the immune adherence test (IAHA). Specific antibodies found by PHA are of the IgM class which indicates a recent exposure to hepatitis A virus. The antibodies found by IAHA reflect the level of postinfectious immune status. The antibody curve is highest in the age group of 30--49 years (95%). The above-mentioned serological tests were carried out with purified by gel filtration in Sepharose 6B Botevgrad faecal morphologically consisting of 27 nm particles with the buoyant density in CcCl of 1.40 g/ml. The same particles were aggregated with sera positive for antibody to hepatitis type A antigen in immune electron microscopy (IEM).
Databáze: MEDLINE