[Dynamics of lipid peroxidation of membranes in cells and mitochondrial fraction of neocortex in non- and preconditioned rats after severe hypobaric hypoxia].

Autor: Kislin MS, Tiul'kova EI, Samoĭlov MO
Jazyk: ruština
Zdroj: Zhurnal evoliutsionnoi biokhimii i fiziologii [Zh Evol Biokhim Fiziol] 2011 Mar-Apr; Vol. 47 (2), pp. 157-64.
Abstrakt: There was studied effect of severe hypobaric hypoxia and subsequent reoxygenation on level and dynamics of lipid peroxidation in membranes of neocortex cells and in mitochondria-enriched neocortex fraction of non-preconditioned rats and of rats preconditioned thrice with a moderate hypobaric hypoxia. The threefold hypoxic preconditioning increasing brain resistance has been shown to significantly prevent disturbance of lipid peroxidation processes in neocortex--one of the most hypoxia-sensitive brain structures--and to modify development of these processes in mitochondria.
Databáze: MEDLINE