[Association between the use of blood components and the five-year mortality after liver transplant].

Autor:	de Morais BS; SBA Organ Transplant Commitee, Anesthesiologist of the Grupo de Transplante of Instituto Alfa de Gastroenterologia/UFMG and Hospital Lifecenter. brunomoraisanest@yahoo.com.br, Sanches MD, Ribeiro DD, Lima AS, de Abreu Ferrari TC, Duarte MM, Cançado GH
Jazyk:	Multiple languages
Zdroj:	Revista brasileira de anestesiologia [Rev Bras Anestesiol] 2011 May-Jun; Vol. 61 (3), pp. 286-92.
DOI:	10.1016/S0034-7094(11)70034-4
Abstrakt:	Background and Objectives: Liver transplant (LT) surgery is associated with significant bleeding in 20% of cases, and several authors have demonstrated the risks related to blood components. The objective of the present study was to evaluate the impact of using blood components during hospitalization in five-year survival of patients undergoing LT. Methods: One hundred and thirteen patients were evaluated retrospectively. Several variables, including the use of blood components intraoperatively and throughout hospitalization, were categorized and evaluated by univariate analysis using Fisher's test. A level of significance of 5% was adopted. Results with p < 0.2 underwent multivariate analysis using multinomial logistic regression. Results: Parenchymal diseases, preoperative renal dysfunction, and longer stay in hospital and ICU are associated with greater five-year mortality after LT (p < 0.05). Unlike the intraoperative use of blood components, the accumulated transfusion of packed red blood cell, frozen fresh plasma, and platelets during the entire hospitalization was associated with greater five-year mortality after liver transplantation (p < 0.01). Conclusions: This study emphasizes the relationship between the use of blood components during hospitalization and increased mortality in five years after LT. (2011 Elsevier Editora Ltda. All rights reserved.)
Databáze:	MEDLINE
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