Treatment of flat or accuminata condylomata of the female genital tract with interferon alpha-2 alpha.
| Autor: | Relakis K; UNIV HERAKLION,DEPT OBSTET & GYNECOL,IRAKLION,GREECE. UNIV PATRAS,DEPT OBSTET & GYNECOL,PATRAS,GREECE. EUROMED MED INST,ATHENS,GREECE. H VENIZELOU MATERN HOSP,DEPT OBSTET & GYNECOL 4,ATHENS,GREECE. ATHENS NAVAL HOSP,DEPT PATHOL,ATHENS,GREECE., Cardamakis E, Korantzis A, Kotoulas I, Stathopoulos E, Metalinos K, Papathanasiou Z, Mantouvalos H, Tzingounis V, Koumantakis E |
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| Jazyk: | angličtina |
| Zdroj: | Oncology reports [Oncol Rep] 1996 Sep; Vol. 3 (5), pp. 951-5. |
| DOI: | 10.3892/or.3.5.951 |
| Abstrakt: | This study was undertaken to assess the effectiveness of Interferon administered parenterally in the treatment of flat or accuminata condylomata of the female genital tract. One hundred and forty-three women with condylomata were treated with CO2 laser vaporization, 5-FU topical application and interferon alpha-2 alpha (IFN alpha-2 alpha) parenterally. The cure rates in the various treatment groups were analysed by the chi-square test. The cure rates of the treatments used in the patients with condylomata accuminata were similar (p>0.1). The best cure rate for flat condylomata was achieved with the combination of CO2 laser vaporization plus 5-FU plus IFN alpha-2 alpha (high dose) (p<0.01). In conclusion, Interferon can be used as adjuvant treatment in patients with recalcitrant condylomata accuminata and as first line treatment in combination with 5-FU and CO2 laser vaporization in patients with flat condylomata. |
| Databáze: | MEDLINE |
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