| Autor: |
Kazemian M; Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Brodsky MH, Sinha S |
| Jazyk: |
angličtina |
| Zdroj: |
Nucleic acids research [Nucleic Acids Res] 2011 Jul; Vol. 39 (Web Server issue), pp. W79-85. Date of Electronic Publication: 2011 May 18. |
| DOI: |
10.1093/nar/gkr291 |
| Abstrakt: |
Genome Surveyor 2.0 is a web-based tool for discovery and analysis of cis-regulatory elements in Drosophila, built on top of the GBrowse genome browser for convenient visualization. Genome Surveyor was developed as a tool for predicting transcription factor (TF) binding targets and cis-regulatory modules (CRMs/enhancers), based on motifs representing experimentally determined DNA binding specificities. Since its first publication, we have added substantial new functionality (e.g. phylogenetic averaging of motif scores from multiple species, and a novel CRM discovery technique), increased the number of supported motifs about 4-fold (from ∼100 to ∼400), added provisions for evolutionary comparison across many more Drosophila species (from 2 to 12), and improved the user-interface. The server is free and open to all users, and there is no login requirement. Address: http://veda.cs.uiuc.edu/gs. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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