Role of whole-body staging computed tomographic scans for detecting distant metastases in patients with bladder cancer.
| Autor: | Rajesh A; Department of Radiology, University Hospitals of Leicester NHS Trust, Leicester General Hospital, Leicester, UK. arajesh27@hotmail.com, Sokhi H, Fung R, Mulcahy KA, Bankart MJ |
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| Jazyk: | angličtina |
| Zdroj: | Journal of computer assisted tomography [J Comput Assist Tomogr] 2011 May-Jun; Vol. 35 (3), pp. 402-5. |
| DOI: | 10.1097/RCT.0b013e318214ad58 |
| Abstrakt: | Objective: This study aimed to establish the incidence of distant metastases on whole-body computed tomographic (CT) scans in patients with newly diagnosed bladder cancer and to determine whether there is a significant difference in the incidence of metastases in patients with superficial and muscle invasive cancers. Materials and Methods: A total of 201 patients who had a proven histological diagnosis of transitional cell carcinoma of the bladder and a whole-body staging CT scan at diagnosis were identified from our MDT database during a 36-month period. Imaging was retrospectively reviewed with view to recording site, if any, of distant metastases. Results: Of 201 patients, 11 (5.5%) were found to have distant metastases on CT. In univariable models, staging was not associated with either age (odds ratio, 0.98; 95% confidence interval, 0.92-1.04; P = 0.4) or sex (Fisher exact test, P = 0.07). Mean (SD) age was 74.1 (10.5) years. There was a significant association between staging and metastasis (odds ratio, 19.9; 95% confidence interval, 3.2-infinity; P = 0.0003). Of the patients, 7% of males had metastases versus 0% of the females. Conclusions: Staging CT scans for assessment of distant metastatic disease in patients with newly diagnosed bladder cancer can be restricted to patients with muscle invasive disease. |
| Databáze: | MEDLINE |
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