[Diagnostic value of alginate test in gastroesophageal reflux disease].
| Autor: | Bordin DS, Masharova AA, Droxzdov VN, Firsova LD, Kozhurina TS |
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| Jazyk: | ruština |
| Zdroj: | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology [Eksp Klin Gastroenterol] 2010 (12), pp. 102-7. |
| Abstrakt: | Aim of Study: To evaluate the diagnostic accuracy of single dose of gaviscon (the alginates test) in detecting gastroesophageal reflux disease (GERD) in patients with heartburn symptoms. Material and Methods: 123 patients (male 46, female 77, age 43.6 +/- 15.5 years) with symptoms suggestive of GERD were investigated. Symptom response to the alginates test compared in GERD positive and GERD negative patients according traditional diagnostic criteria of GERD (upper endoscopy, 24-hr pH-monitoring, esophageal manometry, response to treatment with PPIs). Results: Of 91 (78.9%) patients with positive alginates test, 87 were classified as GERD positive and 4 as GERD negative. Of 32 (26%) patients with negative alginates test, 29 were GERD negative and 3 GERD positive. The results providing a sensitivity of alginates test of 96.7% and a specificity of 87.7%. Conclusions: The alginates test is sensitive and specific for diagnosing GERD in patients with typical GERD symptoms. |
| Databáze: | MEDLINE |
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