Early stages of mesothelioma, screening and biomarkers.

Autor: Klebe S; Department of Anatomical Pathology, Flinders University of South Australia, Adelaide, SA, Australia. sonja.klebe@health.sa.gov.au, Henderson DW
Jazyk: angličtina
Zdroj: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer [Recent Results Cancer Res] 2011; Vol. 189, pp. 169-93.
DOI: 10.1007/978-3-642-10862-4_10
Abstrakt: The early diagnosis of mesothelioma is notoriously difficult, both from a clinical and pathological perspective. Patients often undergo several medical investigations without definitive diagnosis. The discovery of biomarkers that can be assessed in pleural effusions, histological samples, and serum may assist with the difficult early diagnosis of mesothelioma. In this chapter we focus on those markers that have been examined in the setting of either early diagnosis of mesothelioma in symptomatic individuals or that have been proposed as suitable for screening of asbestos-exposed individuals, with an emphasis on cytology and histology.
Databáze: MEDLINE