[Evaluation of clinical, laboratorial and ultrasonographic predicting factors of malignancy in thyroid nodules].

Autor:	Rio AL; Disciplina de Endocrinologia, Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brasil. anario01@hotmail.com, Biscolla RP, Andreoni DM, Camacho CP, Nakabashi CC, Mamone Mda C, Ikejiri ES, Matsumura LK, Hidal JT, Maciel RM, Furlanetto RP
Jazyk:	portugalština
Zdroj:	Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2011 Feb; Vol. 55 (1), pp. 29-37.
DOI:	10.1590/s0004-27302011000100004
Abstrakt:	Objective: To evaluate the risk of malignancy in thyroid nodules through clinical, laboratory, ultrasonographic and cytological aspects. Patients and Methods: 741 nodules of 407 patients. Results: The cytology was benign (60,5%), indeterminate (23,3%), malignant (8,3%) or nondiagnostic (7,6%). The prevalence of cancer in indeterminate citology was 18,5% (16% in follicular lesions, 44% in suspicious). The diagnosis of malignancy was 17,2% (n = 70). The frequency of cancer in women (15,2%) was lower than in men (27,9%). There was an inverse relation between age and cancer risk. There was no statistical significance in the prevalence of cancer according to number, size of nodules or TSH levels. Hypoechogenicity and microcalcifications on ultrasound were risk factors. Conclusion: The risk of malignancy was higher in men, hypoechoic nodules, with microcalcifications and was inversely related to age. The TSH level was not an independent factor predictive of malignancy.
Databáze:	MEDLINE
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