| Autor: |
Altschuler DL; Instituto de Investigaciones en Ingeniería Molecular (INGEBI-CONICET) Buenos Aires, Argentina., Muro A, Schijman A, Almonacid FB, Torres HN |
| Jazyk: |
angličtina |
| Zdroj: |
FEBS letters [FEBS Lett] 1990 Oct 29; Vol. 273 (1-2), pp. 103-6. |
| DOI: |
10.1016/0014-5793(90)81061-r |
| Abstrakt: |
A new member of the ras gene family was characterized from Neurospora crassa cDNA libraries. The clone designated NC-ras codes for a polypeptide containing 213 amino acids (Mr 24,000). This polypeptide is 84% homologous to the H-ras-1 domain comprising the first 80 amino acids and 60% homologous to the next 84 residues. The NC-ras polypeptide contains all the well-known sequences involved in the interaction with GTP/GDP, the recognition of the Y13-259 neutralizing antibody, the 'effector site' for interaction with GAP proteins, and the CAAX acylation motif in the COOH-terminal. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Plný text