Autor: |
Elisee J, Gibson A, Arridge S |
Jazyk: |
angličtina |
Zdroj: |
Biomedical optics express [Biomed Opt Express] 2011 Feb 11; Vol. 2 (3), pp. 568-78. Date of Electronic Publication: 2011 Feb 11. |
DOI: |
10.1364/BOE.2.000568 |
Abstrakt: |
Cortical mapping, also called optical topography is a new medical imaging modality which allows the non-invasive investigation of the outer layers of the cortex. This technique is challenging and the geometry of the subject is very often over-simplified. We aim here to localize activated regions of an anatomically accurate brain. A Boundary Element Method is used for the forward model. The reconstruction of perturbations in the absorption coefficient is demonstrated in a geometrically realistic simulation and in vivo. These results show that diffuse optical imaging of the head can provide reliable activity maps when anatomical data is available. |
Databáze: |
MEDLINE |
Externí odkaz: |
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