Productive performance of the dairy cattle Girolando breed mediated by the fat-related genes DGAT1 and LEP and their polymorphisms.

Autor: Cardoso SR; Laboratório de Nanobiotecnologia, Universidade Federal de Uberlândia, Av. Amazonas, s/n, Bloco 2E, Uberlândia-MG, Brazil., Queiroz LB, Goulart VA, Mourão GB, Benedetti E, Goulart LR
Jazyk: angličtina
Zdroj: Research in veterinary science [Res Vet Sci] 2011 Dec; Vol. 91 (3), pp. e107-12. Date of Electronic Publication: 2011 Mar 10.
DOI: 10.1016/j.rvsc.2011.02.006
Abstrakt: Candidate genes have been associated with milk production in bovines, such as the diacylglycerol O-acyltransferase 1 (DGAT1) and leptin (LEP); however, they have not been simultaneously investigated nor have been evaluated in the Brazilian Girolando breed (Gir×Holstein, backcrossed to Holstein). Our aim was to determine the influence of fat-related genes, DGAT1 and LEP, and their polymorphisms on performance traits of milk production in the Girolando breed. Results indicated that the K allele of the DGAT1 gene showed a significant association with total and average daily milk production with additive effect. The LEP gene showed that the A allele and its homozygote are highly prevalent and almost fixed in this population and may have been favorably selected during backcrossing for the origin of this breed. The important impact of the K allele of the DGAT1 gene on milk production corroborates the initiative of performing marker-assisted selections with this gene in breeding programs of the Girolando breed.
(Copyright © 2011 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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