Prenatal diagnosis and natural history of fetuses presenting with pleural effusion.

Autor: Ruano R; Obstetrics Department, Faculty of Medicine, São Paulo University, São Paulo, Brazil. rodrigoruano@hotmail.com, Ramalho AS, Cardoso AK, Moise K Jr, Zugaib M
Jazyk: angličtina
Zdroj: Prenatal diagnosis [Prenat Diagn] 2011 May; Vol. 31 (5), pp. 496-9. Date of Electronic Publication: 2011 Mar 04.
DOI: 10.1002/pd.2726
Abstrakt: Objective: To describe the natural history of fetuses presenting with pleural effusion.
Methods: Between January 2005 and December 2009 all fetuses diagnosed with pleural effusion were followed up. Fetuses were divided into three groups: I, isolated pleural effusion; II, associated structural anomalies but normal karyotype; and III, chromosomal anomalies. Univariate and multivariate analyses were performed to determine the association between prenatal ultrasound findings and perinatal death.
Results: Fifty-six fetuses were included in the study. Associated structural or chromosomal anomalies occurred in 75.0% (42/56) of cases. Bilateral pleural effusion and fetal hydrops were associated with each other (p < 0.01) and with perinatal death (p < 0.05). Multivariate analysis indicated that only the presence of associated abnormalities was a statistical determinant of perinatal death (OR, 3.56; 95% CI, 1.48-5.64; p < 0.01).
Conclusion: Fetal pleural effusion is often associated with other abnormalities, and this association has poor perinatal outcome.
(Copyright © 2011 John Wiley & Sons, Ltd.)
Databáze: MEDLINE
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