Antimicrobial susceptibility of Neisseria meningitidis strains isolated from meningitis cases in Brazil from 2006 to 2008.
| Autor: | Gorla MC; Division of Medical Biology, Bacteriology Department, Adolfo Lutz Institute, São Paulo, Brazil. mcgorla@ial.sp.gov.br, de Paiva MV, Salgueiro VC, Lemos AP, Brandão AP, Vázquez JA, Brandileone MC |
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| Jazyk: | angličtina |
| Zdroj: | Enfermedades infecciosas y microbiologia clinica [Enferm Infecc Microbiol Clin] 2011 Feb; Vol. 29 (2), pp. 85-9. Date of Electronic Publication: 2011 Feb 22. |
| DOI: | 10.1016/j.eimc.2010.07.016 |
| Abstrakt: | Objective: To analyze the profile of antimicrobial susceptibility of meningococcal disease isolates collected throughout Brazil from 2006 to 2008 and forwarded to the National Reference Laboratory for Meningitis, Institute Adolfo Lutz - São Paulo. Materials and Methods: The MIC to penicillin, ampicillin, chloramphenicol, ceftriaxone, ciprofloxacin and rifampicin was determined in a sample of 1096 (55% of the total isolates received) randomly chosen using the broth microdilution procedure. The breakpoints used were those recommended by the European Monitoring Group on Meningococci (EMGM). Results: Decreased susceptibility to penicillin and ampicillin was detected in 13% and 12.9% respectively. All isolates were susceptible to chloramphenicol, ceftriaxone, and ciprofloxacin. Two strains (0.2%) showed high resistance to rifampicin and 0.5% of the isolates displayed intermediate resistance to rifampicin. Conclusions: The meningococcal strains isolated in Brazil during 2006-2008 were globally susceptible to all antibiotics currently used in treatment or chemoprophylaxis of meningococcal disease in Brazil. (Copyright © 2010 Elsevier España, S.L. All rights reserved.) |
| Databáze: | MEDLINE |
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