| Autor: |
Cosentini V; U.O.C. Nefrologia e Dialisi, Ospedale G. Fracastoro di San Bonifacio, Verona, Italy. enzocos77@libero.it, Cosaro A, Gammaro L, Lidestri V, Oldrizzi L, Maschio G |
| Jazyk: |
italština |
| Zdroj: |
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia [G Ital Nefrol] 2011 Jan-Feb; Vol. 28 (1), pp. 85-8. |
| Abstrakt: |
Emphysematous pyelonephritis is a rare, necrotizing infection of the kidney and the perirenal space resulting in the formation of gas in both structures and associated with a high mortality rate. In 90% of cases it affects one kidney only; in the remaining 10% with bilateral emphysematous pyelonephritis aggressive surgical intervention may be required. Women are much more frequently affected than men, with diabetes mellitus (in 70-90% of cases) and urinary tract obstruction being common predisposing conditions. The pathogenesis of the disease is linked to four main factors: the presence of gasforming bacteria; hyperglycemia; inadequate tissue perfusion; and reduced immune response. Lactose-fermenting bacteria such as Escherichia coli and Klebsiella pneumoniae are the most common infectious agents. We report a case of unilateral emphysematous pyelonephritis due to a ruptured cyst infected by E. coli in a diabetic patient with polycystic kidney disease. The resulting septic shock necessitated an emergency right nephrectomy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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