Positional photocleavage control of DNA-based nanoswitches.
| Autor: | Mok AK; California State Polytechnic University Pomona, Department of Chemistry, 3801 W Temple Avenue, Pomona, CA 91768, USA., Kedzierski NA, Chung PN, Lukeman PS |
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| Jazyk: | angličtina |
| Zdroj: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2011 May 07; Vol. 47 (17), pp. 4905-7. Date of Electronic Publication: 2011 Feb 21. |
| DOI: | 10.1039/c1cc10292c |
| Abstrakt: | DNA-based switches are currently operated by manual solution-phase addition of 'set-strands'. We demonstrate another operation method-sterically inaccessible 'set-strands', released from a surface into solution by spatially controlled photocleavage. This technique will enable microarrays of set-strands to operate many DNA-based switches in self-contained computational and diagnostic devices. (© The Royal Society of Chemistry 2011) |
| Databáze: | MEDLINE |
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