[The therapeutic contribution of proteomic approaches in cancers].
Autor: | Hamrita B; Laboratoire d'immuno-oncologie moléculaire, faculté de médecine de Monastir, 5019 Monastir, Tunisie. bechrhamrita@yahoo.fr, Nasr HB, Kabbage M, Hamann P, Kuhn L, Guillier C, Remadi S, Chaieb A, Khairi H, Chouchane L, Chahed K |
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Jazyk: | francouzština |
Zdroj: | Gynecologie, obstetrique & fertilite [Gynecol Obstet Fertil] 2011 Feb; Vol. 39 (2), pp. 87-93. Date of Electronic Publication: 2011 Feb 12. |
DOI: | 10.1016/j.gyobfe.2010.12.005 |
Abstrakt: | Up to now, there are no protein tumor markers with a specificity and sensitivity sufficient to have a utility in prognosis and early diagnosis of cancer. Recent advances in proteomics approaches have led to the identification of novel tumor markers of cancer that may have a utility in screening strategies and treatment. The purpose of the current review is to describe the major advances in cancer proteomics, especially those related to the study of serum biomarkers, immune-related responses (autoantibodies) and alterations in cellular proteins. (Copyright © 2011 Elsevier Masson SAS. All rights reserved.) |
Databáze: | MEDLINE |
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