| Autor: |
Miller WM; Sanitary Dermatology Department, Professor Rubem David Azulay Dermatology Institute, Santa Casa da Misericórdia Hospital, Rio de Janeiro, Brazil. wmiller@gt.cdc.gov, Gorini F, Botelho G, Moreira C, Barbosa AP, Pinto AR, Dias MF, Souza LM, Asensi MD, da Costa Nery JA |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of STD & AIDS [Int J STD AIDS] 2010 Dec; Vol. 21 (12), pp. 806-9. |
| DOI: |
10.1258/ijsa.2010.010281 |
| Abstrakt: |
The Jarisch-Herxheimer reaction (JHR) is a syndrome observed after antimicrobial treatment of some infectious diseases. The syndrome has clinical characteristics of an inflammatory reaction to antibiotic treatment. A prospective study of patients with a clinical and laboratory diagnosis of syphilis was conducted at a sexually transmitted diseases clinic in Rio de Janeiro, Brazil. Patients were treated with benzathine penicillin and observed for the JHR. A total of 115 patients were included in this study. Fifty-one patients (44%) had secondary syphilis; 37 (32%), primary; 26 (23%), latent; and one (1%), tertiary syphilis. Ten patients (9%) developed the JHR. All JHRs occurred in patients with secondary and latent syphilis. No patients experienced an allergic reaction to penicillin. The JHR occurred less frequently than in previous studies. It is important that health-care professionals recognize the clinical characteristics of the JHR so that it is not misinterpreted as an allergic reaction to penicillin. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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