Clinical outcome of open and laparoscopic surgery in Dukes' B and C rectal cancer: experience from a regional hospital in Hong Kong.

Autor:	Day W; Department of Surgery, Kwong Wah Hospital, 25 Waterloo Road, Hong Kong. weidaday@gmail.com, Lau PY, Li KM, Kwok SY, Yip AW
Jazyk:	angličtina
Zdroj:	Hong Kong medical journal = Xianggang yi xue za zhi [Hong Kong Med J] 2011 Feb; Vol. 17 (1), pp. 26-32.
Abstrakt:	Objective: To compare the long-term outcome of open and laparoscopic surgery for Dukes' B and C rectal cancer in a regional hospital in Hong Kong. Design: Retrospective study. Setting: A regional hospital in Hong Kong. Main Outcome Measures: Survival and local recurrence rates. Patients: Patients with Dukes' B and C rectal cancers underwent elective curative open or laparoscopic surgery during the period December 2000 to December 2006. Results: A total of 222 patients (open surgery, n=133; laparoscopic surgery, n=89) were assessed. The overall 3- and 5-year survival rates for all patients were 72% and 58%, respectively. Local recurrence rates were similar in both groups. Laparoscopic group had better overall survival (P=0.014), however. The overall 3-year survival rates were 79% and 68% in the laparoscopic and open groups, respectively. The corresponding 5-year rates were 75% and 52%. Multivariate analysis also demonstrated that laparoscopic surgery was a significant independent factor for better survival. Chemotherapy, local recurrence, lymph node metastasis, and poorly differentiated tumour were significantly associated with survival. Conclusion: Laparoscopic surgery for Dukes' B and C rectal cancer was associated with more favourable survival than with open surgery.
Databáze:	MEDLINE
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