Clinical and laboratory findings in 220 children with recurrent abdominal pain.

Autor: Gijsbers CF; Department of Paediatric Gastroenterology, Juliana Children's Hospital/Haga Teaching Hospital, The Hague, The Netherlands. c.gijsbers@hagaziekenhuis.nl, Benninga M, Büller H
Jazyk: angličtina
Zdroj: Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2011 Jul; Vol. 100 (7), pp. 1028-32. Date of Electronic Publication: 2011 Feb 22.
DOI: 10.1111/j.1651-2227.2011.02179.x
Abstrakt: Aim:  To investigate the clinical and laboratory findings in children with recurrent abdominal pain (RAP).
Methods: Consecutive patients with RAP (Apley criteria), age 4-16 years, referred to a secondary medical centre were evaluated by a standardized history, physical examination and laboratory tests. The tests encompassed Helicobacter pylori (Hp), gastrointestinal bacterial infections, protozoa, coeliac disease, carbohydrate malabsorption, food intolerance, abdominal ultrasound and plain abdominal X-ray. More investigations were obtained if indicated. Patient characteristics were compared with surgical patients without abdominal pain (control group).
Results: A total of 220 consecutive patients were included (92 M, mean age 8.8 years [4.1-16.0 years]). In 88% of the patients, abnormalities were found that refer to possible causes. Especially, protozoa were present in 33% of the patients, mostly Dientamoeba fragilis, Yersinia enterocolitica in 12% and endoscopically proven infection with Hp in 11%. In 36%, a plain abdominal X-ray raised suspicion of constipation.
Conclusion:   In 220 consecutive patients with RAP, referred to secondary care, a standardized work-up yielded abnormal results in a high percentage. The clinical significance of these findings remains to be established.
(© 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.)
Databáze: MEDLINE
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