Acquired A amyloidosis from injection drug use presenting with atraumatic splenic rupture in a hospitalized patient: a case report.

Autor: Roll GR; Department of Surgery, University of California San Francisco, San Francisco, USA. Garrett.Roll@ucsfmedctr.org., Lee AY, Royaie K, Visser B, Hanks DK, Knudson MM, Roll FJ
Jazyk: angličtina
Zdroj: Journal of medical case reports [J Med Case Rep] 2011 Jan 24; Vol. 5, pp. 29. Date of Electronic Publication: 2011 Jan 24.
DOI: 10.1186/1752-1947-5-29
Abstrakt: Introduction: Little is known about splenic rupture in patients who develop systemic acquired A amyloidosis. This is the first report of a case of atraumatic splenic rupture in a patient with acquired A amyloidosis from chronic injection drug use.
Case Presentation: A 58-year-old Caucasian man with a long history of injection drug use, hospitalized for infective endocarditis, experienced atraumatic splenic rupture and underwent splenectomy. Histopathological and microbiological analyses of the splenic tissue were consistent with systemic acquired A amyloidosis, most likely from injection drug use, that led to splenic rupture without any recognized trauma or evidence of bacterial embolization to the spleen.
Conclusion: In patients with chronic inflammatory conditions, including the use of injection drugs, who experience acute onset of left upper quadrant pain, the diagnosis of atraumatic splenic rupture must be considered.
Databáze: MEDLINE