| Autor: |
Dai C; Department of Chemistry, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA., Narayanam JM, Stephenson CR |
| Jazyk: |
angličtina |
| Zdroj: |
Nature chemistry [Nat Chem] 2011 Feb; Vol. 3 (2), pp. 140-5. Date of Electronic Publication: 2011 Jan 09. |
| DOI: |
10.1038/nchem.949 |
| Abstrakt: |
The development of new means of activating molecules and bonds for chemical reactions is a fundamental objective for chemists. In this regard, visible-light photoredox catalysis has emerged as a powerful technique for chemoselective activation of chemical bonds under mild reaction conditions. Here, we report a visible-light-mediated photocatalytic alcohol activation, which we use to convert alcohols to the corresponding bromides and iodides in good yields, with exceptional functional group tolerance. In this fundamentally useful reaction, the design and operation of the process is simple, the reaction is highly efficient, and the formation of stoichiometric waste products is minimized. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
