| Autor: |
Delaney JL; Department of Chemistry, La Trobe University, Victoria, Australia., Hogan CF, Tian J, Shen W |
| Jazyk: |
angličtina |
| Zdroj: |
Analytical chemistry [Anal Chem] 2011 Feb 15; Vol. 83 (4), pp. 1300-6. Date of Electronic Publication: 2011 Jan 19. |
| DOI: |
10.1021/ac102392t |
| Abstrakt: |
This paper describes the first approach at combining paper microfluidics with electrochemiluminescent (ECL) detection. Inkjet printing is used to produce paper microfluidic substrates which are combined with screen-printed electrodes (SPEs) to create simple, cheap, disposable sensors which can be read without a traditional photodetector. The sensing mechanism is based on the orange luminescence due to the ECL reaction of tris(2,2'-bipyridyl)ruthenium(II) (Ru(bpy)(3)(2+)) with certain analytes. Using a conventional photodetector, 2-(dibutylamino)ethanol (DBAE) and nicotinamide adenine dinucleotide (NADH) could be detected to levels of 0.9 μM and 72 μM, respectively. Significantly, a mobile camera phone can also be used to detect the luminescence from the sensors. By analyzing the red pixel intensity in digital images of the ECL emission, a calibration curve was constructed demonstrating that DBAE could be detected to levels of 250 μM using the phone. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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