Gas chromatographic identification of chlorination products of aliphatic ketones.

Autor: Zenkevich IG; St. Petersburg State University, Chemical Department, Universitetskii Prosp., St. Petersburg 198504, Russia. izenkevich@mail15.com, Eliseenkov EV, Kasatochkin AN, Zhakovskaya ZA, Khoroshko LO
Jazyk: angličtina
Zdroj: Journal of chromatography. A [J Chromatogr A] 2011 May 27; Vol. 1218 (21), pp. 3291-9. Date of Electronic Publication: 2010 Dec 21.
DOI: 10.1016/j.chroma.2010.12.056
Abstrakt: Chlorinated derivatives of aliphatic ketones are a class of organic compounds poorly characterized by both mass spectra and chromatographic retention indices up to present. It is caused by objective difficulties of isolation of individual products from reaction mixtures formed in the result of non-selective chlorination of parent carbonyl compounds. Nevertheless the differences of GC retention indices for structurally analogous chlorination products of different ketones and initial substrates indicate the constancy depending on the number and position of chlorine atoms in the molecules. This feature permits us to use the simplest kind of additive schemes in identification of such chlorinated derivatives, including diastereomeric α,α'-dichloro-k-alkanones (k>2). Hence, the identification of chlorination products of aliphatic ketones becomes possible for any compounds of this class without using mass spectrometric data only in the result of accurate measurement of their GC retention indices.
(Copyright © 2010 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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