[Corticosteroid-induced paranoid psychosis: case report and review of the literature].

Autor:	Seurs L; Universitair Psychiatrisch Centrum KU Leuven, Kortenerg, Belgium. lore.seurs@uc.kortenberg.be, Mierzejewska A, Claes SJ
Jazyk:	Dutch; Flemish
Zdroj:	Tijdschrift voor psychiatrie [Tijdschr Psychiatr] 2011; Vol. 53 (1), pp. 37-47.
Abstrakt:	Background: Our study focuses on a 30-year-old man who was hospitalised against his will because of his agitated psychotic state. His symptoms were indicative of a paranoid psychotic disorder resulting from the use of corticosteroids. We considered it important to report this case because corticosteroids have been widely prescribed since about 1950 to treat a broad spectrum of somatic illnesses and because there have been many reports of both mild and acute psychiatric side-effects. Aim: To obtain answers to the following questions: what is the incidence of steroid-induced psychotic symptoms? Do patients with a psychiatric history run a greater risk of developing a steroid-induced psychosis? What are the most important risk factors and how can we prevent the development of steroid-induced psychotic symptoms? Method: After discussing the case, we studied the literature systematically using Medline. Results: Up till now, very little reliable evidence has been available relating to steroidinduced psychosis. Therefore there has been a lack of information about the incidence of psychotic symptoms caused by steroids, about the risks involved when the patient has a psychiatric history and about the preventive measures that can be taken. Conclusions: The most important risk factor seems to be the dose. Thus, if a patient requires treatment with steroid, it seems advisable to prescribe the lowest possible dose.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu