Autor: |
Srejić R; Institute of General and Physical Chemistry, Belgrade, Yugoslavia., Popov DV, Boricić I, Zuvela M |
Jazyk: |
angličtina |
Zdroj: |
Magnetic resonance in medicine [Magn Reson Med] 1990 Sep; Vol. 15 (3), pp. 469-74. |
DOI: |
10.1002/mrm.1910150313 |
Abstrakt: |
Comparative NMR studies of normal and pathologically altered human stomach tissues were performed on the basis of proton T1 relaxation time measurements in the presence of high external concentrations of relaxation (contrast) agents manganese ethylenediaminetetraacetic acid (Mn-EDTA) and gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA). Diffusion permeability of the cell membrane to water, Pd, was determined by measuring the longest proton T1 component sensitive to the exchange of water molecules through the cell membrane. Pathologically altered tissues showed substantially higher (2 to 10 times) average cell membrane permeabilities to water. |
Databáze: |
MEDLINE |
Externí odkaz: |
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