Control of morbidity due to Schistosoma haematobium on Pemba Island: egg excretion and hematuria as indicators of infection.

Autor: Savioli L; Ministry for Foreign Affairs, Direzione Generale per la Cooperazione allo Sviluppo, Italy., Hatz C, Dixon H, Kisumku UM, Mott KE
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 1990 Sep; Vol. 43 (3), pp. 289-95.
DOI: 10.4269/ajtmh.1990.43.289
Abstrakt: The variability of Schistosoma haematobium egg excretion using a quantitative syringe filtration technique and the variability of hematuria detected visually and by reagent strips were studied in a population of 520 subjects from the village of Pujini (Pemba Island, Zanzibar, Tanzania) for 6 consecutive days. A high degree of day-to-day variability of egg excretion within subjects was found both in the whole population and in the 5-19 year age group. Subjects with 1 urinary egg count of greater than or equal to 50 eggs/10 ml urine were not similarly classified in 36-61% of the other 5 examinations and 4-16% of their other examinations were negative. Gross hematuria had a specificity of almost 100%, when related to a positive filtration on any day, and was closely related to egg counts of greater than or equal to 50 eggs/10 ml urine. The finding of a strongly positive reaction for hematuria on a given single day was closely associated with the subject having a high egg count (greater than or equal to 50 eggs/10 ml urine) on at least one of the 6 days of the study. At the primary health care level, single highly positive semiquantitative values for hematuria were a more useful diagnostic indicator than a single egg count to select patients with heavy infections for selective population chemotherapy.
Databáze: MEDLINE