2-Bromo-methyl-N-isopropyl-7,8-dimeth-oxy-1,2-dihydro-1,3-oxazolo[3,2-a]quinoline-4-carboxamide.

Autor: Shishkina SV, Shishkin OV, Ukrainets IV, Bereznyakova NL, Davidenko AA
Jazyk: angličtina
Zdroj: Acta crystallographica. Section E, Structure reports online [Acta Crystallogr Sect E Struct Rep Online] 2008 May 10; Vol. 64 (Pt 6), pp. o1031. Date of Electronic Publication: 2008 May 10.
DOI: 10.1107/S1600536808013378
Abstrakt: In the title compound, C(18)H(21)BrN(2)O(5), conjugation between the π-donating N-C-O fragment and the π-withdrawing carbonyl group results in considerable redistribution of the electron density within the dihydropyridinol ring. This effect is also promoted by the formation of an intra-molecular N-H⋯O hydrogen bond. The five-membered heterocycle is disordered over two envelope conformations in a 0.35:0.65 ratio.
Databáze: MEDLINE