| Autor: |
Englich U; MacCHESS, Cornell University, Ithaca, NY 14853, USA. ue22@cornell.edu, Kriksunov IA, Cerione RA, Cook MJ, Gillilan R, Gruner SM, Huang Q, Kim CU, Miller W, Nielsen S, Schuller D, Smith S, Szebenyi DM |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of synchrotron radiation [J Synchrotron Radiat] 2011 Jan; Vol. 18 (1), pp. 70-3. Date of Electronic Publication: 2010 Nov 05. |
| DOI: |
10.1107/S0909049510036010 |
| Abstrakt: |
The Macromolecular Diffraction Facility at the Cornell High Energy Synchrotron Source (MacCHESS) is a national research resource supported by the National Center for Research Resources of the US National Institutes of Health. MacCHESS is pursuing several research initiatives designed to benefit both CHESS users and the wider structural biology community. Three initiatives are presented in further detail: microcrystallography, which aims to improve the collection of diffraction data from crystals a few micrometers across, or small well diffracting regions of inhomogeneous crystals, so as to obtain high-resolution structures; pressure cryocooling, which can stabilize transient structures and reduce lattice damage during the cooling process; and BioSAXS (small-angle X-ray scattering on biological solutions), which can extract molecular shape and other structural information from macromolecules in solution. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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