Percutaneous endoscopic gastrostomy/jejunostomy combined with percutaneous transhepatic biliary drainage in treating malignant biliary obstruction.

Autor: Shu JC; Department of Gastroenterology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, PR China., Yang QH, Lv X, Zhang WR, Li ME, Zhang XY, Song HD, Ye GR, Wang LX
Jazyk: angličtina
Zdroj: Medical principles and practice : international journal of the Kuwait University, Health Science Centre [Med Princ Pract] 2011; Vol. 20 (1), pp. 47-50. Date of Electronic Publication: 2010 Dec 13.
DOI: 10.1159/000322073
Abstrakt: Objective: To investigate the safety and efficacy of percutaneous endoscopic gastrostomy/jejunostomy (PEG/PEJ) combined with percutaneous transhepatic biliary drainage (PTCD) in treating malignant biliary obstruction.
Subjects and Methods: Nine patients (6 males and 3 females, average age 71.3 ± 5.5 years) with complete obstruction of the biliary tract were treated with PEG/PEJ after PTCD. The PEG/PEJ and PTCD tubes were linked outside of the abdominal wall to direct the externally drained bile back to the jejunum through the PEG/PEJ intestinal tube. Clinical symptoms and liver function were assessed following the treatment.
Results: The operations were successfully completed in the 9 patients within 40 min (average 35 ± 2.9 min). Clinical symptoms such as jaundice, abdominal distension, stomachache and diarrhea appeared but improved within 7 days of the operation. Serum levels of bilirubin, aspartate aminotransferase and alanine aminotransferase were reduced (p < 0.01) 4 weeks following the treatment. There were no procedural complications.
Conclusions: Combined PEG/PEJ and PTCD appeared to be safe and effective in the management of malignant biliary obstruction. Further, larger-scale studies will be needed to verify findings of this report.
(Copyright © 2010 S. Karger AG, Basel.)
Databáze: MEDLINE