Autor: |
Kulkarni NV; Department of Studies in Chemistry, Karnatak University, Pavate Nagar, Dharwad, Karnataka, India. vkrevankar@rediffmail.com, Budagumpi S, Kurdekar GS, Revankar VK, Didagi S |
Jazyk: |
angličtina |
Zdroj: |
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2010 Dec; Vol. 58 (12), pp. 1569-75. |
DOI: |
10.1248/cpb.58.1569 |
Abstrakt: |
A novel Cu(II) and Zn(II) complexes of triazolo-quinoline derivatives were synthesized by in situ method and were characterized by the spectro-analytical methods and their pharmacological properties were evaluated. The compound C3 has exhibited promising anticonvulsant activity towards the electroshock induced seizures in Wistar rats and possesses low toxicity, providing a high safety profile. |
Databáze: |
MEDLINE |
Externí odkaz: |
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