[Docetaxel as a component in the combined therapy of locally advanced squamous cell carcinoma of the glottis and oral cavity].

Autor: Alieva SB, Tkachev SI, Romanov IS, Zaderenko IA, Tiuliandin SA
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 2010; Vol. 56 (5), pp. 597-602.
Abstrakt: Two modalities of chemoradiotherapy for locally advanced squamous cell cancer of oro-hypopharynx and oral cavity were compared in the treatment of 34 patients. Five-year survival after cisplatin, 5-FU, taxotere, and carboplatin plus irradiation with TTD of 68-72 Gy (group 1) was 59.5% versus 13.8% without taxotere (group 2). Relapse was in 9 cases (60%) (4 - group 1 and 5 - group 2). Post-therapeutic complication stage III-IV was 57.8% (group 1) and 48% (group 2).
Databáze: MEDLINE