[The effect of sterol metabolism in a model ecological system Drosophila-yeasts on the crossing-over in Drosophila].

Autor: Kamilova TA, Luchnikova EM, Inge-Vechtomov SG
Jazyk: ruština
Zdroj: Genetika [Genetika] 1990 Feb; Vol. 26 (2), pp. 249-56.
Abstrakt: The absence of sterols available for metabolism causes the death of Drosophila larva. Addition of suboptimal cholesterol doses to this medium allows the portion of larvae to survive. Sterol-deficient diet at the preimaginal stages leads to suppression of both spontaneous and high-temperature induced crossingover in Drosophila females. Two possible explanations for dependence of recombination process on sterol metabolism are suggested: 1) the shortage of precursor for ecdisons biosynthesis was the cause of discordance of meiotic events; 2) suppression of crossingover occurs, due to alteration of cell membrans' structure.
Databáze: MEDLINE