A new method for the prediction of cervical node metastases in squamous cell carcinoma of the oral cavity: a combination of Martínez-Gimeno Scoring System and clinical palpation.

Autor: Martínez-Gimeno C; Oral and Maxillofacial Surgery Department, Hospital Universitario de Canarias, Carretera La Cuesta-Taco s/n, La Laguna, Santa Cruz de Tenerife, Spain. ortomaxi@yahoo.es, Rodríguez-Delgado LE, Perera-Molinero A, Trujillo Mdel C, Chivite A, Maeso MC, Aguirre-Jaime A
Jazyk: angličtina
Zdroj: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery [J Craniomaxillofac Surg] 2011 Oct; Vol. 39 (7), pp. 534-7. Date of Electronic Publication: 2010 Nov 26.
DOI: 10.1016/j.jcms.2010.10.027
Abstrakt: Aims: Evaluation of the accuracy of palpation, CT scan and Martínez-Gimeno Score System in the assessment of neck nodes metastasis in squamous cell carcinoma of the oral cavity.
Design: This is a prospective triple blind study performed in 40 consecutive patients with squamous cell carcinoma of the oral cavity.
Patients: 40 consecutive patients suffering primary oral squamous cell carcinoma, without any treatment before surgery, palpation or CT Scan.
Results: 40% of the cases showed metastasis in pathological study. Sensitivity was 100%, 94% and 75% for MGSS 13, CT scan and palpation, respectively. Specificity was 83%, 38% and 25-50% for palpation, CT scan and MGSS 13-17, respectively. Negative predictive result values were 100%, 90% and 83% for MGSS 13, CT Scan and palpation. The logistic regression analysis showed an independent predictor factor for palpation (p=0.001) and MGSS (p=0.01). The combination of MGSS and clinical palpation allowed a new design for evaluating neck metastasis in oral cancer. This method establishes 3 different groups at risk: 3 of very low (<2%), 2 of low risk (18-27%) and 1 of high risk (85%).
Conclusions: MGSS predicts metastasis better than CT scan and palpation. Combination of MGSS and palpation improves the prediction of metastasis.
(Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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