| Autor: |
Bruni G; Institute of Pharmacology, University of Siena, Italy., Runci FM, Fiaschi AI, Segre G |
| Jazyk: |
angličtina |
| Zdroj: |
Pharmacological research [Pharmacol Res] 1990 Mar-Apr; Vol. 22 (2), pp. 97-102. |
| DOI: |
10.1016/1043-6618(90)90705-i |
| Abstrakt: |
The differences between the S(+) and R(-) ibuprofen enantiomers in anti-inflammatory activity were assayed by measuring the release of 14CO2 in rats treated with labelled 14COOH-ornithine. Furthermore we investigated in vitro the inhibitory activity on ornithine-decarboxylase and the anti-inflammatory activity of R(-) and S(+) ibuprofen by using the carrageenin-induced paw oedema test in the rat. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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