Autor: |
Radotra B; Department of Medicine, Faculty of Medicine, Charing Cross Campus, Imperial College, London, UK., Apostolopoulos V, Sandison A, Hatfield EC, Mendoza N, Moss J, Mehta A, Glaser M, Meeran K, Roncaroli F |
Jazyk: |
angličtina |
Zdroj: |
Endocrine pathology [Endocr Pathol] 2010 Dec; Vol. 21 (4), pp. 266-73. |
DOI: |
10.1007/s12022-010-9140-9 |
Abstrakt: |
A 29-year-old Ethiopian man presented with marked bilateral visual loss, headache, hypopituitarism and significant hyponatraemia (115 mmol/L). A brain MRI scan demonstrated a large, lobulated, sellar and suprasellar mass, elevating the floor of the 3rd ventricle and compressing the optic chiasm. The patient underwent a transphenoidal resection of the mass followed by a craniotomy 10 days later. Histological examination demonstrated a Hyams' grade III neuroblastoma with ectopic expression of vasopressin. He underwent fractionated radiotherapy at a dose of 60 Gy in 30 fractions. Fourteen months after the onset, he is well with no neuroimaging evidence of tumour recurrence. His serum and urine sodium are completely normalised. |
Databáze: |
MEDLINE |
Externí odkaz: |
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