| Autor: |
Komaki R; Department of Radiotherapy, Columbia Presbyterian Medical Center, New York., Cox JD, Kister SJ, Gump FE, Estabrook A |
| Jazyk: |
angličtina |
| Zdroj: |
Radiology [Radiology] 1990 Jan; Vol. 174 (1), pp. 255-7. |
| DOI: |
10.1148/radiology.174.1.2104676 |
| Abstrakt: |
Between 1980 and 1986, 2,140 patients with surgical stage I or II breast carcinoma were treated including 1,179 patients with T1-2N0 disease and 961 patients with T1-2N1 disease. Among the 1,179 patients without node involvement, 215 underwent limited surgery (complete excision and axillary node dissection) and radiation therapy; 964 patients underwent modified radical mastectomy only. Of the 961 patients with node involvement, 106 were treated by means of limited surgery and radiation therapy; of these, 48 also received chemotherapy. The remaining 855 patients underwent mastectomy; of these, 381 also received chemotherapy and/or hormone therapy. The 5-year survival rates for patients with no node involvement were 96% for the group treated by means of limited surgery and radiation therapy and 88% for the group treated by means of mastectomy (P greater than .05). The 5-year survival rates for patients with node involvement were 96% for the group treated by means of limited surgery and radiation therapy with or without chemotherapy and 77% for the group treated by means of mastectomy with or without chemotherapy (P less than .01). This study demonstrates no disadvantage from treatment by means of limited surgery and radiation therapy and suggests that adjuvant radiation therapy may be important in increasing survival among patients with T1-2 breast carcinoma and positive axillary nodes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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