Seroprevalence of herpes simplex virus type-2 among patients attending the Sexually Transmitted Infections Clinic in Jos, Nigeria.
| Autor: | Agabi YA; Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria. agabiy@unijos.edu.ng, Banwat EB, Mawak JD, Lar PM, Dashe N, Dashen MM, Adoga MP, Agabi FY, Zakari H |
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| Jazyk: | angličtina |
| Zdroj: | Journal of infection in developing countries [J Infect Dev Ctries] 2010 Oct 04; Vol. 4 (9), pp. 572-5. Date of Electronic Publication: 2010 Oct 04. |
| DOI: | 10.3855/jidc.567 |
| Abstrakt: | Background: Infection with Herpes Simplex Virus Type-2 (HSV-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (GUD) worldwide. There is little information on the prevalence of HSV-2 in Nigeria. Methodology: Specimens were collected from 162 volunteers attending Jos University Teaching Hospital and tested for HSV-2 antibodies using HSV-2 Type specific IgG EIA test kit (Globalemed LLC Alexandria VA, USA). Data were analyzed using SPSS version 13.0. P values ≤ 0.05 were considered significant number. Results: Out of the 162 individuals tested, 141 (87.0%) were HSV-2 positive. Infected individuals were more likely to be male than female (92.8% versus 86.4%; P > 0.05). There were high rates of infection in all age groups, and the prevalence increased with age. However, multivariate logistic regression analysis showed that HSV-2 prevalence was not significantly associated with increasing age, sex, marital status, occupation, educational status, and number of sex partners (P > 0.05). Conclusions: The results highlight the potential public health impact of HSV-2 in Nigeria where anti-HSV-2 testing is not generally performed in all populations, especially considering the risk of neonatal transmission and the attendant complications at birth. |
| Databáze: | MEDLINE |
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