Primary cutaneous cryptococcosis caused by Cryptococcus gattii in an immunocompetent host.

Autor: Leão CA; Infectious and Parasitic Diseases Unit, Triangulo Mineiro Federal University, Uberaba, Minas Gerais, Brazil., Ferreira-Paim K, Andrade-Silva L, Mora DJ, da Silva PR, Machado AS, Neves PF, Pena GS, Teixeira LS, Silva-Vergara ML
Jazyk: angličtina
Zdroj: Medical mycology [Med Mycol] 2011 May; Vol. 49 (4), pp. 352-5. Date of Electronic Publication: 2010 Oct 28.
DOI: 10.3109/13693786.2010.530697
Abstrakt: This paper presents the case of a 75-year-old Brazilian man who developed inflammatory skin lesions with nodules and ulcerations on the right forearm after an injury caused by handling barbed-wire and Eucalyptus spp. logs. Histopathological assessment of the lesions showed granulomatous processes with yeasts similar to Cryptococcus spp. Tissue fragments yielded yeasts when cultured that were identified as Cryptococcus gattii VGII through biochemical reactions and URA5-RFLP genotype. No evidence of systemic involvement or any underlying immunosuppressive diseases were identified, which supported the diagnosis of primary cutaneous cryptococcosis. After 5 months on therapy with high fluconazole doses, the skin lesions had fully healed.
Databáze: MEDLINE