Topical treatment of necrotising herpes zoster with betulin from birch bark.

Autor: Weckesser S; Wound care center, Department of Dermatology, University Medical Center Freiburg, Freiburg, Germany., Laszczyk MN, Müller ML, Schempp CM, Schumann H
Jazyk: angličtina
Zdroj: Forschende Komplementarmedizin (2006) [Forsch Komplementmed] 2010 Oct; Vol. 17 (5), pp. 271-3. Date of Electronic Publication: 2010 Sep 09.
DOI: 10.1159/000320592
Abstrakt: Betulin, a pentacyclic triterpene, is the main constituent of the outer bark of birches (Betula alba). In recent years, anti-microbial, anti-inflammatory and differentiation-promoting effects of betulin have been described. A betulin-based emulsion without preservatives and detergent emulsifiers can be prepared from birch bark extract. We report the successful treatment with betulin emulsion of a severe necrotising herpes zoster in an immunosuppressed patient who had not responded to a conventional topical treatment. The betulin emulsion was directly applied to the wounds without causing any side effects. The presented case report demonstrates impressive skin tolerance and wound-healing properties of the betulin emulsion. These should be further evaluated.
(Copyright © 2010 S. Karger AG, Basel.)
Databáze: MEDLINE