Cytotoxicity on L1210 leukemic cells of beta-amanitin-concanavalin A and phallacidin-concanavalin A conjugates.

Autor: Zhelev Z; University School of Medicine, Department of Biology, Stara Zagora, Bulgaria., Ilarionova M, Zheleva A, Alexiev C, Halacheva K, Todorov D
Jazyk: angličtina
Zdroj: Toxicon : official journal of the International Society on Toxinology [Toxicon] 1990; Vol. 28 (11), pp. 1360-3.
DOI: 10.1016/0041-0101(90)90102-d
Abstrakt: The conjugates beta-amanitin-concanavalin A and phallacidin concanavalin A were tested for direct cytotoxicity on L1210 lymphocytic leukemia cells by a combined in vitro-in vivo bioassay. Both conjugates exerted strong direct cytotoxicity on the tumour cells.
Databáze: MEDLINE