[The study of the sensitive and specificity on HBV DNA replication by HBV-lP detecting].

Autor: Shan PN; The Laboratory Center of the Center Hospital of Shaoxing County, Zhejiang Shaoxing 312030, China., Lu ZY, Xuan GH, Weng LM, Ru JC, Tan SH, Xu DS
Jazyk: čínština
Zdroj: Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology [Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi] 2010 Feb; Vol. 24 (1), pp. 68-70.
Abstrakt: Objective: To detect HBV-LP and HBV DNA of the patients with hepatitis B, and to study the sensitive and specificity of HBV-LP detecting and its evaluate on for clinical application.
Methods: The ELISA was used for HBV-LP detecting and RT-PCR for HBV DNA detecting.
Results: The sensitive and specificity of HBV-LP and HBV DNA were 64.89%, 99.68%, 60.63% and 100% respectively (P > 0.05); +LR, -LR were 202.78, 60.63, 0.3522 and 0.3937, and there were significance between +LR of the detecting (P < 0.005).
Conclusion: The sensitive and specificity of HBV-LP and HBV DNA detecting are considerable, +LR of HBV-LP are higher comparing HBV DNA. The HBV-LP is better serology index for detecting replication of HBV DNA.
Databáze: MEDLINE